ʻO Cosmate®HPR10, i kapa ʻia ʻo Hydroxypinacolone Retinoate 10%, HPR10, me ka inoa INCI ʻo Hydroxypinacolone Retinoate a me Dimethyl Isosorbide, ua hoʻokumu ʻia e Hydroxypinacolone Retinoate me Dimethyl Isosorbide, he ester ia o nā all-trans Retinoic Acid, he kūlohelohe a me ka synthetic derivative. ʻO ka huaʻa A, hiki ke hoʻopaʻa i nā mea loaʻa retinoid. Hiki i ka hoʻopaʻa ʻana o nā mea hoʻopaʻa retinoid ke hoʻonui i ka hōʻike gene, ka mea e hoʻohuli maikaʻi i nā hana kelepona nui a i ʻole.