|Mālama ʻIli ʻEpekema Series| Niacinamide (huaʻai B3)

Niacinamide (Ka panacea i ka honua mālama ʻili)

Niacinamide, i ʻike ʻia ʻo vitamin B3 (VB3), ʻo ia ke ʻano hana biologically o ka niacin a loaʻa nui i nā holoholona a me nā mea kanu like ʻole. He mea koʻikoʻi ia o nā cofactors NADH (nicotinamide adenine dinucleotide) a me NADPH (nicotinamide adenine dinucleotide phosphate). Me ka NADH a me NADPH i hoʻemi ʻia, hana lākou ma ke ʻano he coenzymes ma mua o 40 mau hopena biochemical a hana pū kekahi me he antioxidants.

Ma ke kino, hoʻohana nui ʻia e pale a mālama i ka pellagra, stomatitis, glossitis a me nā maʻi e pili ana.

kuleana nui loa
1.Hoʻomaʻamaʻa a hoʻomaʻemaʻe i ka ʻili

Hiki i ka Nicotinamide ke hoʻohaʻahaʻa i ka lawe ʻana i nā melanosomes mai nā melanocytes i keratinocytes me ka ʻole o ka pale ʻana i ka hana tyrosinase a i ʻole ka hoʻonui ʻana o nā cell, a laila e hoʻopilikia ai i ka pigmentation ʻili. Hiki iā ia ke hoʻopilikia i ka pilina ma waena o nā keratinocytes a me nā melanocytes. ʻO nā ala hōʻailona pūnaewele ma waena o nā pūnaewele e hoʻemi i ka hana melanin. Ma ka ʻaoʻao ʻē aʻe, hiki i ka nicotinamide ke hana i ka melanin i hana mua ʻia a hōʻemi i kona neʻe ʻana i nā cell surface.

ʻO kahi manaʻo ʻē aʻe ʻo ka nicotinamide ka hana o ka anti-glycation, hiki ke hoʻoheheʻe i ke kala melemele o ka protein ma hope o ka glycation, he mea kōkua ia no ka hoʻomaikaʻi ʻana i ka ʻili ʻili o nā maka ʻulaʻula a me nā "wahine ʻeleʻele".
E hoʻonui i ka ʻike

Ke hoʻohana ʻia ka niacinamide ma ke ʻano he mea keʻokeʻo, ma ke ʻano o 2% a 5%, ua hōʻoia ʻia i ka maikaʻi i ka mālama ʻana i ka chloasma a me ka hyperpigmentation i hoʻokumu ʻia e nā kukuna ultraviolet.

2.Kūʻē i ka ʻelemakule, hoʻomaikaʻi i nā laina maikaʻi (anti-free radicals)

Hiki i ka Niacinamide ke hoʻoulu i ka collagen synthesis (hoʻonui i ka wikiwiki a me ka nui o ka collagen synthesis), hoʻonui i ka elasticity o ka ʻili, a hoʻemi i ke ʻano o nā laina maikaʻi a me nā wrinkles. Loaʻa iā ia nā waiwai antioxidant e hoʻopau i nā radical manuahi a hoʻolohi i ke kaʻina hana o ka ʻili.
E hoʻonui i ka ʻike

Ua hōʻike nā haʻawina i ka hoʻohana ʻana i ka nicotinamide (5% content) hiki ke hōʻemi i nā wrinkles, erythema, melemele a me nā kiko ma ka ʻili maka.

3.Hoʻoponopono i ka ʻilihana pale
ʻO ka hoʻoponopono ʻana o Niacinamide i ka hana pale ʻili i hōʻike nui ʻia ma nā ʻano ʻelua:

① Hoʻonui i ka synthesis o ka ceramide i ka ʻili;

②Hoʻonui i ka hoʻokaʻawale ʻana o nā keratin cell;
Hiki i ka hoʻohana ʻana i ka nicotinamide ke hoʻonui i nā pae o nā momona momona manuahi a me nā ceramides i ka ʻili, hoʻoulu i ka microcirculation i loko o nā dermis, a pale i ka nalowale o ka ʻili.

Hoʻonui ia i ka synthesis protein (e like me ke keratin), hoʻonui i nā pae intracellular NADPH (nicotinamide adenine dinucleotide phosphate), a hoʻolalelale i ka ʻokoʻa keratinocyte.
E hoʻonui i ka ʻike

ʻO ka hiki ke hoʻomaikaʻi i ka hana pale ʻili i ʻōlelo ʻia ma luna nei, ʻo ia ka niacinamide hiki ke hoʻomaʻemaʻe. Hōʻike nā haʻawina liʻiliʻi he ʻoi aku ka maikaʻi o ka 2% niacinamide topical ma mua o ka petroleum jelly (petroleum jelly) i ka hōʻemi ʻana i ka wai o ka ʻili a me ka hoʻonui ʻana i ka hydration.

ʻO ka hui maikaʻi o nā meaʻai
1. ʻO ka hui ʻana o ka hoʻomaʻemaʻe a me ka wehe ʻana i ka freckle: niacinamide +ʻO ka retinol A
2. Hoʻohui pū ʻana i ka moisturizing hohonu:hyaluronic acid+ squalane