Ferulic acidhe hui kūlohelohe i loaʻa i loko o nā ʻano mea kanu like ʻole Angelica sinensis, Ligusticum chuanxiong, horsetail a me nā lāʻau lapaʻau kuʻuna Kina, a ua loaʻa ka manaʻo no kāna mau waiwai pono. Loaʻa ia i loko o ka ʻili laiki, nā pī pandan, ka palaoa palaoa a me ka laiki. Loaʻa i kēia ʻakika ʻawaʻawa nāwaliwali kahi ʻano phenolic acid a hana ʻo ia ma ke ʻano he mea paʻa tyrosinase. Ke hui pū ʻia me nā antioxidants ikaika e like me resveratrol ahuaʻai C, he nui nā pono o ka ferulic acid e like me ke keʻokeʻo o ka ʻili, ka pale antioxidant, ka pale ʻana i ka lā, a me nā hopena anti-inflammatory.
ʻO kekahi o nā mana kupaianaha o ka ferulic acid ʻo kāna mau waiwai antioxidant. ʻO kāna ʻano phenolic hydroxyl e hana maikaʻi i nā radical manuahi, me nā radical superoxide a me nā radical hydroxyl. Ma ka hopu ʻana i ka lua o nā electron mai nā radical manuahi, hoʻopaʻa ka ferulic acid i ka mole a poloka i ka hoʻoili electron, e pale ana i ke kino mai ka pōʻino oxidative. Eia kekahi, he pilina ikaika ka ferulic acid no Fe2 +, kahi e hoʻoulu ai i ka hopena redox a hoʻemi i ka Fe2 +, e pāʻani ana i kahi kuleana nui i ka hana antioxidant. ʻO ka mea hoihoi, ʻoi aku kona hiki ke hōʻemi i nā pūhui Fe3+ ma mua o kohuaʻai C.
Ma waho aʻe o kāna mau pono antioxidant, ʻo ka ferulic acid kekahi mau waiwai keʻokeʻo. ʻAʻole ʻae wale ka hui i ka hana melanocyte B16V akā pale pū kekahi i ka hana tyrosinase, e hāʻawi ana i kahi ala ʻelua i ka loaʻa ʻana o ka ʻili keʻokeʻo. ʻO kahi hopena i loaʻa ka 5 mmol/L ferulic acid i kāohi i ka hana tyrosinase e kahi 86%. ʻOiai ma kahi haʻahaʻa haʻahaʻa o 0.5mmol/L, ua hōʻike mau ka ferulic acid i ka nui o ka inhibition rate ma kahi o 35% ma ka hana tyrosinase.
Eia kekahi, loaʻa i ka ferulic acid nā waiwai pale o ka lā. Mālama ʻo ia i ka ʻili mai nā kukuna ʻino o ka lā, e hāʻawi ana i kahi ʻāpana pale hou aku i ka pōʻino o ka lā. Hana kēia i mea hoʻohui kūpono i lokopale lānā huahana a me nā ʻano hana mālama ʻili ʻē aʻe i hoʻolālā ʻia e hōʻemi i nā pilikia ʻili pili i ka UV.
ʻO ka hope, ua hōʻike ʻia ka ferulic acid i nā waiwai anti-inflammatory. Ma ka ho'ēmiʻana i ka mumū, hiki ke kōkua i ka hoʻomahaʻana i nā maʻi o kaʻili e like me kaʻulaʻula, ka huhū, a me ka pehu. No laila, ʻo ka hoʻohui ʻana i ka ferulic acid i nā huahana mālama ʻili e kōkua i ka olakino a me ka maikaʻi o ka ʻili.
I ka hōʻuluʻuluʻana, loaʻa ka ferulic acid i ka nui o nā mea kanu a me nā kumu kūlohelohe a he nui nā pono no ka ʻili. Mai ka mana antioxidant ikaika a hiki i ke keʻokeʻo, pale i ka lā a me nā waiwai anti-inflammatory, ʻo ka ferulic acid kahi mea hoʻohui e hiki ke hoʻonui i ka pono o nā huahana mālama ʻili a hoʻoikaika i ka ʻili olakino.
Ka manawa hoʻouna: ʻOkakopa-30-2023
