ʻO ka anti-inflammatory a me ka antioxidant e pili ana i nā ʻaoʻao ʻelua - ka mea mālama ʻili maoli, phloretin！

1.-He aha ka phloretin-

Phloretin(Inoa Pelekania: Phloretin), i ʻike ʻia he trihydroxyphenolacetone, no nā dihydrochalcones ma waena o nā flavonoids. Hoʻopili ʻia i loko o nā rhizomes a i ʻole nā ​​aʻa o nā ʻāpala, nā strawberries, nā pears a me nā huaʻai ʻē aʻe a me nā mea kanu like ʻole. Ua kapa ʻia ma muli o ka ʻili. Hiki ke hoʻoheheʻe ʻia i ka hopena alkali, hiki ke hoʻoheheʻe ʻia i ka methanol, ethanol a me ka acetone, a aneane hiki ʻole ke hoʻoheheʻe ʻia i ka wai.

Hiki ke hoʻopili pololei ʻia ka phloretin e ke kino o ke kanaka, akā i loko o nā mea kanu, he liʻiliʻi loa ka phloretin kūlohelohe. Loaʻa ka phloretin ma ke ʻano o kāna glycoside derivative, phlorizin. ʻO ka phloretin i hoʻopili ʻia e ke kino o ke kanaka aia i ka mucosa ʻōpū. Ma hope wale nō o ka wehe ʻia ʻana o ka pūʻulu glycoside e hoʻohua i ka phloretin hiki iā ia ke komo i ka ʻōnaehana kaʻa a hoʻokō i kona hopena.

Ka inoa kemika: 2,4,6-trihydroxy-3-(4-hydroxyphenyl)propiophenone

Huina mole: C15H14O5

Kaumaha molekula: 274.27

2.-Na hana nui o ka phloretin-

anti-oxidation

Loaʻa i nā Flavonoids ka hana anti-fat oxidation, i hoʻopaʻa ʻia e like me ka 1960s: hiki i nā hale polyhydroxyl o nā flavonoids ke loaʻa i nā waiwai antioxidant koʻikoʻi ma ka chelating me nā ion metala.

ʻO Phloretin kahi antioxidant kūlohelohe maikaʻi loa. He hopena antioxidant maikaʻi loa ka ʻōnaehana 2,6-dihydroxyacetophenone. Loaʻa iā ia kahi hopena ʻike i ka scavenging peroxynitrite a he kiʻekiʻe ka nui o ka antioxidant i loko o nā aila. Ma waena o 10 a me 30PPm, hiki iā ia ke wehe i nā radical manuahi i ka ʻili. Hoʻemi nui ʻia ka hana antioxidant a Phlorizin no ka mea ua hoʻololi ʻia kāna hui hydroxyl ma ke kūlana 6 e kahi pūʻulu glucosidyl.
Kāohi i ka tyrosinase

ʻO Tyrosinase kahi metalloenzyme i loaʻa i ke keleawe a he enzyme nui i ka hana ʻana o ka melanin. Hiki ke hoʻohana ʻia ka hana tyrosinase e loiloi inā he hopena keʻokeʻo ka huahana. ʻO Phloretin kahi mea hoʻopaneʻe hui ʻia o tyrosinase. Hiki iā ia ke pale i ka tyrosinase mai ka hoʻopaʻa ʻana i kāna substrate ma o ka hoʻololi ʻana i ke ʻano lua o tyrosinase, a laila e hōʻemi ana i kāna hana catalytic.

Ka hana antibacterial

ʻO Phloretin kahi pūhui flavonoid me ka hana antibacterial. Loaʻa iā ia nā hopena pale i nā ʻano bacteria Gram-positive, Gram-negative bacteria a me nā fungi.
Hōʻike nā hopena hoʻokolohua lapaʻau ma hope o ka hoʻohana ʻana o nā kumuhana i ka phloretin no 4 mau pule, ua hoʻemi nui ʻia nā poʻo keʻokeʻo, nā ʻeleʻele, nā papules, a me ka sebum huna, e hōʻike ana he hiki i ka phloretin ke hoʻomaha i ka haki.

3. ʻO nā mea i manaʻo ʻia
ʻano nui
2% phloretin(antioxidant, keʻokeʻo) + 10% [l-ʻakika ascorbic] (antioxidant, hoʻolaha collagen a me keʻokeʻo) + 0.5%ʻakika ferulic(antioxidant and synergistic effect), hiki ke pale aku i nā kukui ultraviolet i ke kaiapuni , infrared radiation a me ka ozone pōʻino i ka ʻili, hoʻomālamalama i ka ʻili o ka ʻili, a ʻoi aku ka maikaʻi no ka ʻili ʻaila me ka leo ʻili ʻili.